Erythema multiforme - Erythema Multiform
☆ Mune 2022 Stiftung Warentest mhedzisiro kubva kuGermany, kugutsikana kwevatengi neModelDerm kwakangodzikira zvishoma pane nekubhadharwa kwe telemedicine kubvunzana.
Erythema multiforme minor ― Ziva kuti nzvimbo dzemaronda dzinogona kuputika.
Urticaria inogonawo kutorwa seyakasiyana kuongororwa.
References
Erythema multiforme (EM) imamiriro ekuti akasarudzika-akange makwapa anoonekwa paganda uye mucous membranes nekuda kwemaitiro ekudzivirira. Kunyange zvazvo kazhinji ichikonzerwa nehutachiona hwehutachiona, kunyanya herpes simplex virus (HSV) , kana mamwe mishonga, chikonzero chinoramba chisingazivikanwi muzviitiko zvakawanda. Kurapa acute EM kunotarisa kurerutsa zviratidzo uchishandisa makirimu ane steroid kana antihistamines. Kugadzirisa inodzokororwa EM kunonyanya kushanda kana yakagadzirirwa kumurwere wega wega. Nzira dzekutanga dzinosanganisira kurapa kwemuromo uye kwepamusoro. Izvi zvinosanganisira corticosteroids uye antiviral mishonga. Kurapa kwepamusoro kunosanganisira yakasimba steroid creams uye mhinduro dzeakakanganisika mucous membranes. Kune varwere vasingadaviri kumishonga inorwisa mavhairasi, sarudzo dzemutsara wechipiri dzinosanganisira mishonga inodzvanya muviri, mishonga inorwisa mabhakitiriya, anthelmintics, uye marariya.
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Muzviitiko zvakawanda, hunyoro erythema multiforme inoenda yega mukati memavhiki maviri kusvika mana. Stevens-Johnson syndrome, chirwere chakakomba chinokanganisa mucous membranes, chinogona kugara kusvika kumavhiki matanhatu. Steroids haiwanzo kurudzirwa kune zvinyoro nyoro. Kana steroids inofanira kushandiswa kune yakanyanya erythema multiforme haina chokwadi sezvo pasina zvakajeka zvakawanikwa kubva kuongororo dzakarongwa dzinoratidza kuti ndevapi vana vangabatsirwa nekurapa uku.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
Isu tinopa nyaya yemuromo erythema multiforme (EM) yakakonzerwa ne TMP/SMX , inoratidza maronda emumuromo nemuromo pasina maronda eganda. Izvi zvinosimbisa kukosha kwekuisiyanisa kubva kune mamwe maoral ulcerative kusagadzikana. Murwere akawana kurapwa kwechiratidzo uye mapiritsi eprednisolone, zvichiita kuti pave nekuvandudzwa mushure mekumisa TMP/SMX therapy.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
Erythema multiforme kuita kunosanganisira ganda uye dzimwe nguva mucosa, inokonzereswa ne immune system. Kazhinji, inotaridza senge maronda anovavarirwa, anogona kuita seakasarudzika, kudzoka, kana kuramba. Aya maronda anowanzo symmetrically kukanganisa magumo, kunyanya nzvimbo dzawo dzekunze. Zvikonzero zvikuru zvinosanganisira kutapukira kwakadai seherpes simplex virus uye Mycoplasma pneumoniae, pamwe nemimwe mishonga, majekiseni, uye autoimmune zvirwere. Kusiyanisa erythema multiforme kubva kune urticaria inotsamira pane nguva yezvironda; erythema multiforme maronda anoramba akagadziriswa kwemazuva manomwe, ukuwo maronda eurticaria achiwanzopera mukati mezuva. Kunyangwe zvakafanana, zvakakosha kusiyanisa erythema multiforme kubva kune yakanyanya kusimba yeStevens-Johnson syndrome, iyo inowanzo ratidza kupararira erythematous kana purpuric macules ane mablister. Kugadzirisa erythema multiforme kunosanganisira kuzorora kwechiratidzo netopical steroids kana antihistamines uye kugadzirisa chiri kukonzera. Kune zviitiko zvinowanzoitika zvakabatana neherpes simplex virus, prophylactic antiviral therapy inokurudzirwa. Kubatanidzwa kwakanyanya kwemucosal kungada kuchipatara kune intravenous fluid uye electrolyte kutsiva.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Mamiriro acho anosiyana kubva pakupfava, kuzvimisikidza kusvika kune yakaoma, inotyisidzira hupenyu fomu inozivikanwa se erythema multiforme huru iyo inosanganisirawo mucous membranes. Kupinda kwemukasi membrane kana kuvapo kwemabhuru zviratidzo zvakakosha zvekuomarara.
- Erythema multiforme minor: zvakajairika zvinangwa kana kusimudzwa, edematous papules akagoverwa acrally
Chimiro chakapfava chinowanzo ratidza nekukwenya zvinyoro nyoro (asi kukwenya kunogona kuve kwakanyanya), mabhururu epingi-tsvuku, akarongeka akarongwa uye achitangira kumagumo. Kugadziriswa kwekuputika mukati memazuva 7-10 ndiyo inowanzoitika mumhando iyi yechirwere.
- Erythema multiforme major: zvakajairika zvinangwa kana kusimudzwa, edematous papules akagoverwa acrally nekubatanidzwa kweimwe kana akawanda mucous membranes. Epidermal detachment inosanganisira isingasviki 10% yenzvimbo yese yemuviri.
○ Kurapa ― OTC Zvinodhaka
Kana iri pamwe chete nefivha (kukwira kwekushisa kwemuviri), zvinokurudzirwa kushanyira chipatara nokukurumidza.
Mishonga inofungidzirwa kuti inofanira kurega. (semuenzaniso maantibiotic, nonsteroidal anti-inflammatory drugs)
Oral antihistamines yakadai secetirizine uye loratadine yekukwenya.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]